Junk DNA: a journey through the dark matter of the genome
(Book)

Book Cover
Published:
New York : Columbia University Press, [2015].
Format:
Book
Physical Desc:
viii, 340 pages : illustrations ; 24 cm.
Status:
ASU Main (3rd floor)
QH447 .C37 2015
Copies
Location
Call Number
Status
Last Check-In
ASU Main (3rd floor)
QH447 .C37 2015
On Shelf
Feb 18, 2017
Citations
APA Citation (style guide)

Carey, N. (2015). Junk DNA: a journey through the dark matter of the genome. New York: Columbia University Press.

Chicago / Turabian - Author Date Citation (style guide)

Carey, Nessa. 2015. Junk DNA: A Journey Through the Dark Matter of the Genome. New York: Columbia University Press.

Chicago / Turabian - Humanities Citation (style guide)

Carey, Nessa, Junk DNA: A Journey Through the Dark Matter of the Genome. New York: Columbia University Press, 2015.

MLA Citation (style guide)

Carey, Nessa. Junk DNA: A Journey Through the Dark Matter of the Genome. New York: Columbia University Press, 2015. Print.

Note! Citation formats are based on standards as of July 2010. Citations contain only title, author, edition, publisher, and year published. Citations should be used as a guideline and should be double checked for accuracy.
Description

For decades after the indentification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases. Our increasing knowledge of junk DNA has led to innovative research and treatment approaches that may finally ameliorate some of these conditions. Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. These functions have forced scientists to revisit the very meaning of the word "gene" and have endangered a spirited scientific battle over whether or not this genomic "nonsense" is the source of human biological complexity. Drawing on her experience with leading scientific investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, and evolution. We are only now unlocking the secrets of junk DNA, and Nessa Carey's book is an essential resource for navigating the history and controversies of this fast-growing, hotly disputed field. -- from dust jacket.

Also in This Series
More Like This
More Details
Language:
English
ISBN:
9780231170840, 023117084X

Notes

Bibliography
Includes bibliographical references (pages [289]-328) and index.
Description
For decades after the indentification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases. Our increasing knowledge of junk DNA has led to innovative research and treatment approaches that may finally ameliorate some of these conditions. Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. These functions have forced scientists to revisit the very meaning of the word "gene" and have endangered a spirited scientific battle over whether or not this genomic "nonsense" is the source of human biological complexity. Drawing on her experience with leading scientific investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, and evolution. We are only now unlocking the secrets of junk DNA, and Nessa Carey's book is an essential resource for navigating the history and controversies of this fast-growing, hotly disputed field. -- from dust jacket.
Other Editions and Formats
More Copies In Prospector
Loading Prospector Copies...
Staff View
Grouped Work ID:
66fe2f2b-da95-de65-f7b1-ffb945d1c73a
Go To GroupedWork

Record Information

Last Sierra Extract TimeJun 19, 2020 10:43:40 AM
Last File Modification TimeSep 07, 2020 02:26:36 AM
Last Grouped Work Modification TimeJul 31, 2021 08:02:02 PM

MARC Record

LEADER05063cam a2200649 i 4500
001ocn899332106
003OCoLC
00520150912040625.0
008150107s2015    nyua     b    001 0 eng  
010 |a 2014955417
0167 |a 101657482|2 DNLM
019 |a 913091213
020 |a 9780231170840|q (hardback)
020 |a 023117084X|q (hardback)
020 |z 9780231539418 (e-book)
035 |a (OCoLC)899332106|z (OCoLC)913091213
040 |a NLM|b eng|e rda|c NLM|d YDXCP|d BDX|d BTCTA|d ABG|d MNJ|d WKM|d VP@|d SHH|d ZQP|d OCLCF|d GYG|d CLZ
042 |a nlmcopyc
049 |a CLZA
05014|a QH447|b .C37 2015
08204|a 572.86|2 23
1001 |a Carey, Nessa,|0 http://id.loc.gov/authorities/names/n2011183962|e author.
24510|a Junk DNA :|b a journey through the dark matter of the genome /|c Nessa Carey.
264 1|a New York :|b Columbia University Press,|c [2015]
300 |a viii, 340 pages :|b illustrations ;|c 24 cm.
336 |a text|b txt|2 rdacontent.
337 |a unmediated|b n|2 rdamedia.
338 |a volume|b nc|2 rdacarrier.
504 |a Includes bibliographical references (pages [289]-328) and index.
5050 |a An introduction to genomic dark matter -- Why dark matter matters -- When dark matter turns very dark indeed -- Where did all the genes go? -- Outstaying an invitation -- Everything shrinks when we get old -- Two is the perfect number -- Painting with junk -- Playing the long game -- Adding colour to the dark matter -- Why parents love junk -- Junk with a mission -- Switching it on, turning it up -- No man's land -- Project ENCODE : Big Science comes to junk DNA -- Headless queens, strange cats, and portly mice -- Lost in translation -- Why LEGO is better than Airfix -- Mini can be mighty -- The drugs do work (sometimes) -- Some light in the darkness -- Appendix. Human diseases in which junk DNA has been implicated.
520 |a For decades after the indentification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases. Our increasing knowledge of junk DNA has led to innovative research and treatment approaches that may finally ameliorate some of these conditions. Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. These functions have forced scientists to revisit the very meaning of the word "gene" and have endangered a spirited scientific battle over whether or not this genomic "nonsense" is the source of human biological complexity. Drawing on her experience with leading scientific investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, and evolution. We are only now unlocking the secrets of junk DNA, and Nessa Carey's book is an essential resource for navigating the history and controversies of this fast-growing, hotly disputed field. -- from dust jacket.
65012|a Genome, Human.|0 https://id.nlm.nih.gov/mesh/D015894.
65022|a DNA.|0 https://id.nlm.nih.gov/mesh/D004247.
65022|a Genomics.|0 https://id.nlm.nih.gov/mesh/D023281.
650 0|a Genomics.|0 http://id.loc.gov/authorities/subjects/sh2002000809.
650 0|a Human genome.|0 http://id.loc.gov/authorities/subjects/sh94002900.
650 0|a Eukaryotic cells.|0 http://id.loc.gov/authorities/subjects/sh85045546.
650 0|a Recombinant DNA.|0 http://id.loc.gov/authorities/subjects/sh85111851.
650 0|a Insertion elements, DNA.|0 http://id.loc.gov/authorities/subjects/sh85066708.
650 0|a Non-coding RNA.|0 http://id.loc.gov/authorities/subjects/sh2006003525.
650 0|a Gene therapy.|0 http://id.loc.gov/authorities/subjects/sh85053738.
650 7|a Eukaryotic cells.|2 fast|0 (OCoLC)fst00916456.
650 7|a Gene therapy.|2 fast|0 (OCoLC)fst00939638.
650 7|a Genomics.|2 fast|0 (OCoLC)fst00940228.
650 7|a Human genome.|2 fast|0 (OCoLC)fst00963101.
650 7|a Insertion elements, DNA.|2 fast|0 (OCoLC)fst00974201.
650 7|a Non-coding RNA.|2 fast|0 (OCoLC)fst01741020.
650 7|a Recombinant DNA.|2 fast|0 (OCoLC)fst01091466.
907 |a .b49240304|b as |c -|d 150912|e 200619
998 |a as|b 150912|c m|d a |e -|f eng|g nyu|h 0|i 1
948 |a MARCIVE Comp, 2019.05
948 |a MARCIVE August, 2017
948 |a MARCIVE extract Aug 5, 2017
994 |a C0|b CLZ
995 |a Loaded with m2btab.ltiac in 2019.05
995 |a Loaded with m2btab.ltiac in 2017.09
989 |a QH447 .C37 2015|d as |b 1010002174271|e 02-08-2017 8:59|f  - - |g - |h 6|i 3|j 18|k 150912|l $0.00|m  |n 02-18-2017 14:55|o -|p 61|q 61|t 0|x 0|1 .i99586976