While investigating a murder on his ranch, Hank finds himself as the number one suspect. Hank heads for the hills and becomes an outlaw, where he is befriended by band of coyotes. Then they unveil a plan to raid Hank's ranch.
Duped into thinking the world is coming to an end, Hank the Cowdog winds up in town for some more adventures including getting in and out of a case of "soap hydrophobia."